Prince of Songkla University, the first university in Southern Thailand, was established in 1966 in Tambon Ruesamilae, Mueang District, Pattani Province. Initially, it was named the "University of Southern Thailand."

The Parliament passed the Prince of Songkla University Act, which came into effect on March 13. As a result, Prince of Songkla University designated March 13 as its Foundation Day. The university is committed to the development of Southern Thailand, guided by an educational framework that supports economic and social growth, promotes harmony and equality, and serves as a source of academic and community services for both urban and rural areas.